Medically reviewed by Anju Goel, MD The Food and Drug Administration (FDA) has approved a handful of sleep medications that can be alternatives to Ambien (zolpidem). Hetlioz (tasimelteon), Neupro (rotigotine transdermal system), and Silenor (doxepin) can treat specific sleep disorders like insomnia. Over-the-counter (OTC) sleep aids like melatonin …