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Mets vs. Brewers odds, predictions: MLB picks, best bets Wednesday

Clay Holmes will lead the Mets to a win over the Brewers in the first game of the teams’ split doubleheader on Wednesday afternoon.
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Hero dad on Disney cruise did not place daughter on railing before her horrifying plunge, investigation reveals

The father of a 5-year-old girl who fell overboard from a Disney cruise ship off the coast of Florida did not lift her up onto the railing before the accident, authorities have said. A 5-year-old girl fell overboard on Disney a cruise before her dad jumped into the ocean after her. The dad was treading…
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The Troubled Global Energy Transition

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Dalai Lama defies China to say successor will be chosen by Tibetan tradition

Spiritual leader challenges Beijing in video statement released in run-up to 90th birthday celebrations

The Dalai Lama has declared in a direct challenge to China that the centuries-old spiritual institution bearing his name will continue after his death and that only his inner circle, not Beijing, will have the authority to identify his successor.

In a video message played on Wednesday during prayer celebrations ahead of his 90th birthday this weekend, the 14th Dalai Lama said the Gaden Phodrang Trust, which manages his affairs, would oversee the search for his reincarnation.

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French police arrest ‘incel’ suspected of planning knife attack on women

Detention of 18-year-old man part of anti-terror police force’s first case linked to involuntary celibate movement

An 18-year-old French man who claimed affiliation with the misogynist “incel” movement has been arrested and placed under formal investigation on suspicion of planning attacks targeting women, France’s national anti-terrorist prosecutor’s office (PNAT) has said.

The arrest on Wednesday was part of PNAT’s first case linked to the “incel” (involuntary celibate) movement, an online network of men motivated to engage in violence against women whom they believe unjustly reject their sexual or romantic advances.

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Lobster bisque and onion soup on ISS menu for French astronaut

Chef with 10 Michelin stars has designed meals for Sophie Adenot’s trip to International Space Station next year

Even by the exacting standards of France’s gastronomes, it sounds like a meal that is truly out of this world. When the French astronaut Sophie Adenot travels to the International Space Station next year, she will dine on French classics such as lobster bisque, foie gras and onion soup prepared specially for her by a chef with 10 Michelin stars.

Parsnip and haddock velouté, chicken with tonka beans and creamy polenta, and a chocolate cream with hazelnut cazette flower will also be on the menu, the European Space Agency said on Wednesday.

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Tourism sector warns of US risks, price pressures and staff shortages

Fáilte Ireland’s snapshot of the tourism industry shows growing challenges behind the growth
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President and Taoiseach lead tributes to Brother Kevin Crowley

Brother Kevin died peacefully shortly after 10am on Wednesday morning at the Holy Trinity on Fr Matthew Quay in Cork city.
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Live updates: House GOP set to tackle Senate’s work on Trump megabill

Debate on President Trump’s tax policy bill returns to the House on Wednesday, a day after the Senate narrowly passed the legislation at the end of a contentious debate. The House Rules Commi…
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Vertex Gets EU Nod for New Cystic Fibrosis Drug Alyftrek

Vertex Pharmaceuticals VRTX announced that the European Commission has approved Alyftrek (deutivacaftor/tezacaftor/vanzacaftor) for treating people with cystic fibrosis (“CF”) aged six years and above having at least one non-class I mutation in the cystic fibrosis transmembrane conductance regulator (“CFTR”) gene. Alyftrek is a combination of three drugs — vanzacaftor (a CFTR potentiator), deutivacaftor (a CFTR corrector) and tezacaftor. The…